Endocrine Abstracts

Objective and aims: This study was designed to investigate the clinical characteristics of a representative group of type 1 diabetic (T1D) population in Castilla La Mancha, a region in central Spain. The aim of this report is to evaluate the relationship between the educational level and cardiometabolic risk in adult patients with T1D.Patients and methods: This is an observational, cross-sectional, prospective and multicentre study of 1465 patients who r...

Background: One of the main drawbacks of primary treatment of Graves’ disease (GD) with thionamide drugs (TD) is the high relapse rate estimated to be 50–60%. Fear about side effects, specially agranulocitosis and hepatic complications, is other drawback of this treatment option.Objective: To evaluate the clinical and/or biochemical characteristics that might predict relapse in patients with GD treated with TD.Design and ...

Background: Thyroid carcinoma is the most common endocrine malignancy. BRAF (V600E) mutation is the most frequent detected genetic change in papillary thyroid carcinomas (PTC). There are some discrepancies regarding the overall frequency of the mutation, its prevalence in PTC-variants and its relationship with clinicopathological parameters of poor outcome.Aims: To investigate the relationship of clinicopathological features of PTC with BRAF mutation wit...

Background and aims: DIACAM1 study was designed to investigate the clinical characteristics of a representative group of type 1 diabetic (T1D) population in Castilla-La Mancha (Spain). The aim of this report is to describe the prevalence of microvascular complications and the factors associated with such complications.Materials and methods: This is an observational, cross-sectional, prospective and multicentre study of 1465 patients who received assistan...

Objective: Our objective in this study was to identify the type of clinical care received by young type 1 diabetic patients who have made the transition from paediatric to adult care, and to assess the metabolic status of the patients. The research aimed to develop a sustainable and coordinated approach to facilitating the transition between diabetes services for adolescents and reveal from the perspective of the adolescents living with type 1 diabetes their experiences surrou...

Somatostatin receptors (sst1–sst5) comprise a family of G-protein-coupled, 7 transmembrane domain (TMD) receptors encoded by five separate, intronless genes widely distributed throughout the organism. Somatostatin (SST) and cortistatin (CORT), two highly-related cyclic neuropeptides, bind to sst1–sst5 with comparable subnanomolar affinity to exert a number of (patho)physiological actions, from inhibition of endocrine secretions (e.g. GH and insulin), to the control o...

Objective: To report a rare case of papillary thyroid carcinoma (PTC) in a thyroglossal duct cyst (TGDC).Case report: A 34-year-old peruvian male came to our hospital with a complaint of a swelling cervical mass in the anterior central side of the neck, which was growing since 6 months earlier. The patient had no significant past medical, surgical history and was completely asymptomatic. He denied any family history of thyroid disease or history of head ...